Subtle is a low-dose botanical formula crafted for sensitive nervous systems and first-time microdosers seeking calm, clarity, and reconnection — without risking overwhelm.
At its core is saffron, one of the most studied botanicals for emotional well-being. Clinical trials have shown saffron to be as effective as leading antidepressants in improving symptoms of low mood, anxiety, and PMS — without the side effects. It supports healthy serotonin levels, lifts the emotional baseline, and nourishes the nervous system at a root level.
Complementing this is blue lotus, a sacred flower traditionally used in Egyptian medicine for its heart-opening and anxiolytic effects. Known for gently enhancing mood, softening reactivity, and bringing the body into a state of open receptivity, blue lotus helps you stay present and regulated as you begin or resume your microdosing path.
Whether you’re just beginning or returning after a pause, Subtle was made to meet you gently — with grace, not force.
Serving size: 1 Capsules | 20 Capsules per bottle (one month supply)
Ideal for those who have:
*Excluded from additional discounts and promo codes
**Note: Our first batch will ship in our classic packaging, as our beautiful new paper tube design is currently in production and arriving soon.
Mindful Nootropic (20 mg) Gentle neuroplasticity, subtle emotional awareness—true micro.
Lion’s Mane (250 mg) Supports nerve regeneration, clarity, and long-term brain health.
Saffron Extract (2% Safranal 3% Crocin) (14 mg) Clinically backed for mood, withdrawal support, serotonin modulation.
Blue Lotus Flower (25mg) For nervous system nourishment. Adds a calming, heart-opening effect. Gently rounds out psilocybin’s edge.
2 Days On /1 Day Off.
Take for 4–6 weeks, then break for a week to reset and integrate.
Avoid taking on an empty stomach to avoid any potential gut discomfort.
For best results, take after a light, protein-rich breakfast with a full glass of water and 3 deep breaths.
0–30 minutes:
30–90 minutes:
90 minutes–4 hours:
Subtle is intentionally gentle — ideal for sensitive systems, first-timers, or anyone wanting to support neuroplasticity, emotional balance, and nervous system regulation without overstimulation.
We use a clinically aligned saffron extract standardized for safranal and crocin—the key bioactive compounds shown to improve mood, cognition, and stress response.
Saffron doesn’t just boost serotonin. It appears to modulate multiple neurotransmitters, reduce neuroinflammation, and support the gut-brain axis—making it the perfect botanical partner for low-dose psilocybin.
Saffron is one of the most expensive and sought-after botanicals in the world—and for good reason. It takes over 75,000 Crocus sativus flowers to produce just one pound of saffron, making it more valuable by weight than gold.
Mood Elevation: Clinical trials have shown saffron to be as effective as leading antidepressants like fluoxetine (Prozac) and imipramine in supporting mood—without the harsh side effects.
Anxiety + Emotional Exhaustion: A 2020 study in healthcare workers found saffron reduced symptoms of burnout and anxiety, while boosting motivation and engagement.
Focus and Attention: Research in adolescents and adults with attention challenges showed measurable improvements in concentration, hyperactivity, and working memory.
Saffron vs. Fluoxetine (2019):
Saffron extract was as effective as Prozac for treating mild-to-moderate depression.
Read the study
Saffron and Burnout Recovery (2021):
Saffron may be particularly relevant for increasing resilience against the development of stress-related psychiatric disorders
Read the study
Saffron and Sleep Quality (2023)
Saffron can improve nervous functions such as sleep quality and anxiety as confirmed in all the included studies in this systematic review.
Read the study
Saffron in the treatment of depression and anxiety (2018):
Saffron exerts antidepressant effects comparable to those of pharmaceutical antidepressants with possibly fewer observed side effects
Read the study
Saffron in ADHD (2022):
Saffron combination therapy with Ritalin can effectively improve symptoms of patients with ADHD.
Read the study
Ritual-worthy, rigorously sourced, and consistently potent.
Supports neuroplasticity, emotional insight, and the rewiring of entrenched patterns. At this threshold dose, it opens new perspectives without overriding the body’s cues.
Supporting the brain’s structural integrity—encouraging nerve growth, myelination, and long-term cognitive function.
Helps to open the heart and quiet the mind. Blue Lotus gently cushions the edge of psilocybin and adds a serene, embodied layer to the experience.